Stan,
PML can present in many ways so any new neurological symptoms in patients on natalizumab should be evaluated by an experienced neurologist. But often the earliest symptoms are cognitive and can consist of word finding difficulty, memory dysfunction, confusion, followed by gait ataxia, vision problems, etc.
Even though a patient is JCV antibody negative, he should still be evaluated for PML if any new symptoms or worsening of old symptoms. We must remain vigilant. Particularly now that treatments are also improving for PML.
I hope this helps.
Best
tim
Timothy Vollmer, MD
Professor of Neurology
Medical Director-RMMSC
Co-Director-RMMSC at Anschutz
Sunday
The Multiple Sclerosis Intimacy and Sexuality Questionnaire — re-validation and development of a 15-item version with a large US sample
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| Timothy Vollmer, MD |
The Multiple Sclerosis Intimacy and Sexuality Questionnaire
Background: Sexual dysfunction is common in multiple sclerosis (MS) but reliable and valid measurement in this population is needed.
Objective: The objective of this research is to re-validate the Multiple Sclerosis Intimacy and Sexuality Questionnaire-19 in a large US sample.
Methods: A total of 6300 MS patients from the NARCOMS registry completed the MSISQ-19. Unforced principal component analysis utilizing
oblique rotation with Kaiser Normalization validated its construct validity.
oblique rotation with Kaiser Normalization validated its construct validity.
Conclusion: The revised 15-item MSISQ is a reliable and valid measure of sexual dysfunction in men and women with MS.
- Frederick W Foley1,2
- Vance Zemon1
- Denise Campagnolo6
- Ruth Ann Marrie3
- Gary Cutter4
- Tuula Tyry5
- Meghan Beier1
- Eileen Farrell1
- Timothy Vollmer6
- Laura Schairer1
- 1Yeshiva University, Ferkauf Graduate School of Psychology, USA
- 2Holy Name Medical Center, Multiple Sclerosis Center, USA
- 3Department of Internal Medicine, University of Manitoba, Canada
- 4Department of Biostatistics, University of Alabama at Birmingham, USA
- 5Barrow Neurological Institute, USA
- 6Rocky Mountain Multiple Sclerosis Center, University of Colorado Hospital, USA
- Frederick W. Foley, Ferkauf Graduate School of Psychology, Yeshiva University, 1300 Morris Park Avenue, Bronx, New York 10461, USA. Email: ffoley1@aol.com
Friday
TIMOTHY L. VOLLMER, MD: CURRICULUM VITAE
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TIMOTHY L. VOLLMER, MD
|
CURRICULUM VITAE
Clinical Practice
Dr. Vollmer sub-specializes in multiple sclerosis. He has a special interest in immunotherapies for MS. Dr. Vollmer is Medical Director of the Rocky Mountain Multiple Sclerosis Center, and Co-Director of the RMMSC at Anschutz, which provides a multidisciplinary approach to treatment of this disease. He sees patient at the Anschutz Centers for Advanced Medicine.
Timothy Vollmer, M.D., Professor of Neurology, University of
Colorado Denver, School of Medicine, is Co-Director of the Rocky Mountain MS Center at Anschutz Medical Campus and Medical Director of the Rocky Mountain MS Center.
Widely recognized as one of the world’s leading experts in multiple sclerosis, Dr. Vollmer brings 26 remarkable years of experience to the Rocky Mountain MS Center. In addition to serving as Medical Director, Dr. Vollmer has also joined the faculty of the University of Colorado School Denver of Medicine.
Dr. Vollmer’s relocation to Colorado follows six years as the Van Denburgh Professor at Barrow Neurological Institute (BNI) in Phoenix, Arizona where he served as Director of the Neuroimmunology
and MS Programs.
He built BNI’s MS Program to include a large clinic, an active lab investigating antigen-based therapies, a vibrant clinical research program, and an international registry collecting data on over 32,000 patients.
Under his leadership, the Institute’s MS Program was honored as a Center of Excellence by the Consortium of MS Centers.
Dr. Vollmer received his doctorate of medicine from Stanford University School of Medicine and is a former faculty member of Yale School of Medicine.
Widely recognized as one of the world’s leading experts in multiple sclerosis, Dr. Vollmer brings 26 remarkable years of experience to the Rocky Mountain MS Center. In addition to serving as Medical Director, Dr. Vollmer has also joined the faculty of the University of Colorado School Denver of Medicine.
Dr. Vollmer’s relocation to Colorado follows six years as the Van Denburgh Professor at Barrow Neurological Institute (BNI) in Phoenix, Arizona where he served as Director of the Neuroimmunology
and MS Programs.
He built BNI’s MS Program to include a large clinic, an active lab investigating antigen-based therapies, a vibrant clinical research program, and an international registry collecting data on over 32,000 patients.
Under his leadership, the Institute’s MS Program was honored as a Center of Excellence by the Consortium of MS Centers.
Dr. Vollmer received his doctorate of medicine from Stanford University School of Medicine and is a former faculty member of Yale School of Medicine.
To learn about Dr. Vollmer’s research, please click here
Tuesday
My Educational Video on MS and MS Trials
CLICK HERE TO WATCH MY VIDEO
Timothy Vollmer, MD
Co-Director, Rocky Mountain MS Center at Anschutz
Medical Director, Rocky Mountain MS Center
Director, Neurology Clinical Research
Professor, Department of Neurology, University of Colorado
Wednesday
Dr. Vollmer is the Co-Director of the Rocky Mountain MS Center Anschutz Center at the University of Colorado
Welcome to the 2013 DIGITAL Winter Issue of InforMS,
the Rocky Mountain MS Center magazine.
InforMS is now delivered in two digital formats: a page-turning format and
a PDF version that is printable.
If you are subscribed to the printed version--it will be arriving in a couple of weeks!
PDF version (3 MB) (Printable)
Digital, page-turning issue.
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